Ku Wyrazistej Ekspresji1 towards Clear Expression
نویسنده
چکیده
The text presents the objects of contemporary architecture, creating a new category of aesthetic "architectural icons". Such buildings appearing in different moments of history, become an expression of a new approach to design theory, express the novelty of his time, creating new monuments and are not suitable to follow.
منابع مشابه
Assessment of adaptive response of gamma radiation in the operating room personnel exposed to anesthetic gases by measuring the expression of Ku 80, Ligase1 and P53 genes
Introduction: Staffs of operating room are continuously exposed to anesthetic gases and ionizing radiation. Adaptive response, as a defense mechanism, will occur when cells become exposed to a low dose of factors harming DNA that causes in the next exposures to higher doses o...
متن کاملModulation of thermal induction of hsp70 expression by Ku autoantigen or its individual subunits.
Previously, we proposed a dual control mechanism for the regulation of the heat shock response in mammalian cells: a positive control mediated by the heat shock transcription factor HSF1 and a negative control mediated by the constitutive heat shock element-binding factor (CHBF). To study the physiological role of CHBF in the regulation of heat shock response, we purified CHBF to apparent homog...
متن کاملKu protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks.
Ku protein binds to DNA ends and is a cofactor for the DNA-dependent protein kinase. Both of these components are involved in DNA double-strand break repair, but it has not been clear if they function indirectly, by sensing DNA damage and activating other factors, or if they are more directly involved in the processing and rejoining of DNA breaks. We demonstrate that intermolecular ligation of ...
متن کاملImpact of the Ku Complex on HIV-1 Expression and Latency
Ku, a cellular complex required for human cell survival and involved in double strand break DNA repair and multiple other cellular processes, may modulate retroviral multiplication, although the precise mechanism through which it acts is still controversial. Recently, Ku was identified as a possible anti-human immunodeficiency virus type 1 (HIV-1) target in human cells, in two global approaches...
متن کاملNeuronal expression of the DNA repair protein Ku 70 after ischemic preconditioning corresponds to tolerance to global cerebral ischemia.
BACKGROUND AND PURPOSE Oxidative stress after ischemia/reperfusion has been shown to induce DNA damage and subsequent DNA repair activity. Ku 70/86, multifunctional DNA repair proteins, bind to broken DNA ends and trigger a DNA repair pathway. We investigated the involvement of these proteins in the development of neuronal tolerance to global cerebral ischemia after ischemic preconditioning. ...
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تاریخ انتشار 2015